Ophiuroidine, the first indolo[2,1-b]quinazoline alkaloid from the Caribbean brittle star Ophiocoma riisei |
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| Authors: | Natalia K Utkina Vladimir A Denisenko |
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| Institution: | Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, 690022 Vladivostok, Russia |
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| Abstract: | A new indoloquinazoline alkaloid, ophiuroidine 1, having an indolo2,1-b]quinazoline-6,12-dione skeleton, was isolated from the Caribbean ophiuroid, Ophiocoma riisei. The structure of 1 was determined as 4,8,9-trihydroxyindolo2,1-b]quinazoline-6,12-dione from spectroscopic data. Ophiuroidine 1 is the first example of an indoloquinazoline alkaloid found in a marine invertebrate. |
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| Keywords: | Echinoderms Ophiuroids Alkaloids Antioxidants Indolo[2 1-b]quinazoline Tryptanthrine |
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