A microwave improvement in the synthesis of the quinazoline scaffold |
| |
| Authors: | Adriana Chilin Giovanni Marzaro Samuele Zanatta Adriano Guiotto |
| |
| Affiliation: | Department of Pharmaceutical Sciences, University of Padova, Via Marzolo, 5, 35131 Padova, Italy |
| |
| Abstract: | A rapid and efficient microwave-assisted protocol is described that greatly improves a recent synthetic method developed for quinazoline synthesis. The synthetic protocol is based on the use of cycles of microwave irradiation. The optimization process is reported and the experimental results are compared with those of the conventional synthetic route. |
| |
| Keywords: | Quinazoline Microwave-assisted synthesis Irradiation cycles |
| 本文献已被 ScienceDirect 等数据库收录！ |
