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A chiral ketone for enantioselective recognition of 1,2-amino alcohols
Authors:Raju Nandhakumar
Affiliation:Department of Chemistry and Division of Nano Sciences, Ewha Womans University, Seoul 120-750, South Korea
Abstract:A novel auxillary chiral ketone has been designed, synthesized, and used to enantioselectively recognize 1,2-amino alcohols. This work proves that the keto group can serve as a chiral recognition center by imine formation supported by resonance assisted hydrogen bonding (RAHB).
Keywords:Chiral ketone   Enantioselective recognition   1,2-Amino alcohols   Imine bond
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