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Rumphellatin A, the first chloride-containing caryophyllane-type norsesquiterpenoid from Rumphella antipathies |
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| Authors: | Ping-Jyun Sung Li-Fan Chuang Jimmy Kuo Tung-Yung Fan Wan-Ping Hu |
| Affiliation: | a National Museum of Marine Biology and Aquarium, Checheng, Pingtung 944, Taiwan, ROC b Institute of Marine Biotechnology, National Dong Hwa University, Checheng, Pingtung 944, Taiwan, ROC c Institute of Marine Biodiversity and Evolution, National Dong Hwa University, Checheng, Pingtung 944, Taiwan, ROC d Faculty of Biotechnology, Kaohsiung Medical University, Kaohsiung 807, Taiwan, ROC |
| Abstract: | A novel chloride-containing 14C norsesquiterpenoid, rumphellatin A (1), was isolated from the Formosan gorgonian coral Rumphella antipathies. The structure of metabolite 1 was determined on the basis of spectral data analysis and the configuration of 1 was further supported by molecular mechanics calculations. Rumphellatin A (1) showed activity against Gram-negative bacteria. |
| Keywords: | Rumphellatin Caryophyllane Norsesquiterpenoid Rumphella Antibacterial activity |
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