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Ruthenium-catalysed conversion of 1,4-alkynediols into pyrroles
Authors:Simon J. Pridmore
Affiliation:Department of Chemistry, University of Bath, Claverton Down, Bath BA2 7AY, UK
Abstract:Various 1,2,5-substituted pyrroles have been synthesised from 1,4-alkynediols using a ruthenium catalysed isomerisation to give the corresponding 1,4-dicarbonyl compounds, which undergo in situ cyclisation to pyrroles in the presence of amine.
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