Sulfamic acid: an efficient, cost-effective and recyclable solid acid catalyst for the three-component synthesis of α-amino nitriles |
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| Authors: | Akbar Heydari Mehrdad Pourayoubi Ali Reza Mahjoub |
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| Institution: | Chemistry Department, Tarbiat Modarres University, PO Box 14115-175, Tehran, Iran |
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| Abstract: | α-Amino nitriles are synthesized by the three-component coupling reaction of aldehydes, amines and trimethylsilyl cyanide using sulfamic acid as a heterogeneous solid acid catalyst, under solvent-free conditions in excellent yields. The catalyst was recovered by simple filtration and was recycled in subsequent reactions. |
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| Keywords: | α-Amino nitriles Sulfamic acid Trimethylsilyl cyanide Reusable |
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