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Synthesis of novel highly functionalized biologically active polycyclic caged amides
Authors:Beena James  Soumini Mathew  Divya Lakshmanan
Institution:a Organic Chemistry Section, Chemical Sciences Division, National Institute for Interdisciplinary Science and Technology (CSIR), Trivandrum 695 019, India
b Department of Molecular Microbiology, Rajiv Gandhi Centre for Biotechnology, Trivandrum 695 014, India
Abstract:The synthesis of novel polycyclic amides has been achieved through the reaction of bishalomethyl pentacyclo5.4.0.02,6.03,10.05,9]undecane diones with acyclic and cyclic secondary amines in the presence of an ionic liquid. Three of the compounds prepared have been found to possess antituberculosis activity.
Keywords:
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