Synthesis of novel highly functionalized biologically active polycyclic caged amides |
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Authors: | Beena James Soumini Mathew Divya Lakshmanan |
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Institution: | a Organic Chemistry Section, Chemical Sciences Division, National Institute for Interdisciplinary Science and Technology (CSIR), Trivandrum 695 019, India b Department of Molecular Microbiology, Rajiv Gandhi Centre for Biotechnology, Trivandrum 695 014, India |
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Abstract: | The synthesis of novel polycyclic amides has been achieved through the reaction of bishalomethyl pentacyclo5.4.0.02,6.03,10.05,9]undecane diones with acyclic and cyclic secondary amines in the presence of an ionic liquid. Three of the compounds prepared have been found to possess antituberculosis activity. |
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