a Discovery Research, Dr. Reddy’s Laboratories Ltd, Bollaram Road, Miyapur, Hyderabad 500 049, AP, India b Chemistry Division, Institute of Science and Technology, JNT University, Kukatpally, Hyderabad 500 072, AP, India
Abstract:
A synthesis of the C1-C12 fragment of amphidinolide T1 utilising Evans’ aldol, oxy-Michael and cross metathesis reactions as the key steps is described.