a School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332, USA b Department of Physical and Earth Sciences, School of Chemistry, Jacksonville State University, Jacksonville, AL 36265, USA
Abstract:
The tandem synthesis of naphthoquinones was conducted from the reaction of laccase-generated quinones and acyclic dienes via Diels-Alder reaction. This reaction was carried out under mild condition in aqueous medium and yielded naphthoquinones up to 80%. In addition, the effect of solvent was also investigated and water was shown to be optimal for this reaction.