Direct catalytic asymmetric aldol reactions of aldehydes |
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Authors: | Bøgevig Anders Kumaragurubaran Nagaswamy Jørgensen Karl Anker |
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Affiliation: | Center for Metal Catalyzed Reactions, Department of Chemistry, Aarhus University, DK-8000, Aarhus C, Denmark. |
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Abstract: | The development of a direct catalytic enantioselective aldol reaction of aldehydes with activated carbonyl compounds catalyzed by chiral amines is presented and the potential demonstrated by the synthesis of optically active beta-hydroxycarboxylic acid derivatives. |
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