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Lipophilic derivatives of cyclam as new inhibitors of tumor cell growth
Authors:Sibert John W  Cory Ann H  Cory Joseph G
Institution:Department of Chemistry, University of Texas at Dallas, P.O. Box 830688, Richardson, TX 75083-0688, USA. sibertj@utdallas.edu
Abstract:Two new lipophilic tetraazamacrocycles were prepared and, in contrast to non-lipophilic analogs, found to be potent inhibitors of tumor cell growth in vitro with IC50 values below 10 micromolar.
Keywords:
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