In vivo cleavage of a target RNA by copper kanamycin A. Direct observation by a fluorescence assay |
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| Authors: | Chen Chun-An Cowan J A |
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| Affiliation: | Evans Laboratory of Chemistry, Ohio State University, 100 West 18th Avenue, Columbus, Ohio 43210, USA. |
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| Abstract: | A novel fluorescence assay to monitor in vivo cleavage chemistry of RNA target sequences has been established and used to demonstrate the activity of copper aminoglycoside mediated degradation of RNA in bacterial cells. |
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