Direct conversion of macrocyclic furans into macrocyclic isothiazoles |
| |
Authors: | Guillard Jérôme Meth-Cohn Otto Rees Charles W White Andrew J P Williams David J |
| |
Affiliation: | Chemistry Department, University of Sunderland, Sunderland, UK SR1 3SD. |
| |
Abstract: | The first calixhetarenes with more than one heteroatom in the constituent rings are prepared in one step by treatment of calix[4]furan 1a and calix[6]furan 1b with ethyl carbamate, thionyl chloride and pyridine to give 2, 3, 4 and 5, 6, 7 respectively; these products have been characterised by X-ray crystallography which reveals that in 2 all eight heteroatoms lie on one face of the macrocyle. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|