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Combinatorial development of chiral phosphoramidite-ligands for enantioselective conjugate addition reactions
Authors:Huttenloch Oliver  Laxman Eltepu  Waldmann Herbert
Affiliation:Max-Planck-Institut für molekulare Physiologie, Abteilung Chemische Biologie, Otto-Hahn-Str. 11, 44227 Dortmund, Germany.
Abstract:Chiral phosphoramidite ligands embodying bispidine frame work and a binaphthyl phosphoramidite for Cu-catalysed enantioselective conjugate addition reactions were developed employing principles of combinatorial and solid phase chemistry.
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