Autoinductive exponential signal amplification: a diagnostic probe for direct detection of fluoride |
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Authors: | Perry-Feigenbaum Rotem Sella Eran Shabat Doron |
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Institution: | School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel. |
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Abstract: | A new example of an exponential signal amplification strategy for the direct detection of fluoride is demonstrated. The amplification occurred through reaction of fluoride with a responsive chromogenic probe. The probe activity is based on a unique dendritic chain reaction that generates a fluoride anion, which is the analyte of interest, during the disassembly pathway of the dendritic probe. This autoinductive amplification mechanism may be applied for detection of other analytes by coupling activity of a modified probe with that of the fluoride amplifier. |
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Keywords: | analytes dendrimers dyes/pigments fluoride reaction mechanisms |
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