Cell adhesive spectra along surface wettability gradient from superhydrophilicity to superhydrophobicity |
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Authors: | Jingxin Meng Gao Yang Lu Liu Yongyang Song Lei Jiang Shutao Wang |
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Institution: | 1.CAS Key Laboratory of Bio-inspired Materials and Interfacial Science, CAS Center for Excellence in Nanoscience, Technical Institute of Physics and Chemistry,Chinese Academy of Sciences,Beijing,China;2.University of Chinese Academy of Sciences,Beijing,China |
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Abstract: | Surface wettability is important to design biointerfaces and functional biomaterials in various biological applications. However, to date, it remains some confusions about how cells would response to the surfaces with different wettabilities. Herein, we systematically explore the adhesive spectra of cells to the surface with wettability gradient from superhydrophilicity to superhydrophobicity, clarifying the effect of wettability on cell adhesion. We envision that this study may provide valuable information for the design of biomedical implants with controllable cell adhesion, such as neural interface devices and flexible implant. |
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