| 量子点的荧光共振能量转移在生物分析中的应用 |
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| 引用本文： | 马慧莲,刘含智,王丽萍,徐淑坤,李惟. 量子点的荧光共振能量转移在生物分析中的应用[J]. 分析化学, 2005, 33(9): 1335-1338 |
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| 作者姓名： | 马慧莲 刘含智 王丽萍 徐淑坤 李惟 |
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| 作者单位： | 东北大学理学院,沈阳,110004;吉林大学生命科学学院,长春,130023;吉林大学生命科学学院,长春,130023;东北大学理学院,沈阳,110004 |
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| 基金项目： | 吉林省长春市振兴老工业基地科技攻关项目 |
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| 摘 要： | 量子点良好的光谱特性和自身优点，使其可以作为生物荧光探针，而替代传统荧光染料。近年来这方面的研究已经取得了一定的进展。目前，量子点在共振能量转移方面的研究，进一步扩展了它在生物分析中的应用。介绍了量子点基于共振能量转移原理在生物分析中的应用，即利用量子点设计的两种类的蛋白-蛋白特异性结合分析和3种生物传感器的模型设计。
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| 关 键 词： | 量子点 荧光共振能量转移 生物荧光探针 生物分析 评述 |
| 收稿时间： | 2004-04-22 |
| 修稿时间： | 2004-04-222004-07-28 |
Application of Fluorescence Resonance Energy Transfer of Quantum Dots in Biological Assay |
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| Ma Huilian,Liu Hanzhi,Wang Liping,Xu Shukun,Li Wei. Application of Fluorescence Resonance Energy Transfer of Quantum Dots in Biological Assay[J]. Chinese Journal of Analytical Chemistry, 2005, 33(9): 1335-1338 |
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| Authors: | Ma Huilian Liu Hanzhi Wang Liping Xu Shukun Li Wei |
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| Affiliation: | 1.College of Science, Northeastern University, Shenyang 110004;2.College of Life Science, Jilin University, Changchun 130023 |
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| Abstract: | In recent years, quantum dots(QDs) have been investigated as biological fluorescent probes in place of organic dyes, because of their better spectral feature and inherent functional advantages. Now the potential uses of QDs in bio-labeling had been expanded through their ability to participate in fluorescence resonance energy transfer(FRET). In this paper, the FRET-based studies of QDs in biological assay, two types of protein-protein specific binding assay and three types of biological sensors are introduced. |
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| Keywords: | Quantum dot fluorescence resonance energy transfer luminescent biological fluorescent probe biological assay review |
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