Hindered rotation of CH3 groups and phenyl ring in clofibric acid (drug) studied by35Cl-NQR and1H-NMR spectroscopy |
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| Authors: | B Nogaj J W?sicki M Mendlikowska-Humerczyk A Glaser R Utrecht |
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| Institution: | 1. Institute of Physics, Adam Mickiewicz University, Poznań, Poland
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| Abstract: | The35C1-NQR frequency (VQ), nuclear quadrupole spin-lattice relaxation time (T1Q),1H-NMR second moment (M 2), nuclear magnetic spin-lattice relaxation time (T 1) and spin-lattice relaxation time in rotating frame (T 1p ) were measured for polycrystalline clofibric acid (drug) as a function of temperature. Hindered rotation of two dynamically inequivalent methyl groups and the phenyl ring was detected, the relevant activation energies were determined. The rotations are discussed in detail. |
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