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ESR study of some asymmetric-triazine copper(II) complexes having high antiviral activity |
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| Authors: | C. G. Palivan H. M. N. Palivan B. A. Goodman C. Cristescu |
| Affiliation: | 1. Department of Atomic and Nuclear Physics, University of Bucharest, Bucharest-Magurele, Romania 2. Scottish Crop Research Institute, Invergowrie, Dundee, UK 3. Chemical and Pharmaceutical Research Institute, Bucharest, Romania |
| Abstract: | Electron paramagnetic resonance (EPR) spectroscopy and molecular dynamics calculations have been used to compare the chemical environments of Cu(II) in three substituted asymmetric-triazine (as-triazine) complexes with a closely related complex that was reported previously to have Superoxide dismutase (SOD) and antiviral activities. The structure most strongly associated with the biological activity appears to be planar with two 6-membered chelate rings having 2N2O coordination around the copper atom. |
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