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Two new 5‐deoxyflavan‐3,4‐diol glucosides from roots of Albizia chevalieri
Authors:Abdou Tchoukoua  Turibio Kuiate Tabopda  Shota Uesugi  Ken‐ichi Kimura  Eunsang Kwon  Hiroyuki Momma  Bonaventure Tchaleu Ngadjui  Takuya Koseki  Yoshihito Shiono
Affiliation:1. Département de Chimie Organique, Université de Yaoundé 1, Yaoundé, Cameroun;2. Department of Food, Life, and Environmental Science, Faculty of Agriculture, Yamagata University, Tsuruoka, Yamagata, Japan;3. The United Graduate School of Agricultural Sciences, Iwate University, Morioka, Iwate, Japan;4. Research and Analytical Center for Giant Molecules, Graduate School of Science, Tohoku University, Sendai, Miyagi, Japan
Abstract:Phytochemical investigation of the roots of Albizia chevalieri led to the isolation of two new 5‐deoxyflavan‐3,4‐diol glucosides from roots of A. chevalieri, Chevalieriflavanosides A and B. Their structures were established by 2D NMR techniques, UV, IR, CD, and mass spectrometry. Cytotoxicity of the two compounds was evaluated against acute promyelocytic leukemia HL60 cells. The antibacterial activities of 1 and 2 also were evaluated against Pseudomonas aeruginosa and Staphylococcus aureus using the agar diffusion test. Copyright © 2016 John Wiley & Sons, Ltd.
Keywords:NMR  1H  13C  Leguminosae  Albizia chevalieri  flavan‐3,4‐diols  cytotoxicity
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