Two new 5‐deoxyflavan‐3,4‐diol glucosides from roots of Albizia chevalieri |
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Authors: | Abdou Tchoukoua Turibio Kuiate Tabopda Shota Uesugi Ken‐ichi Kimura Eunsang Kwon Hiroyuki Momma Bonaventure Tchaleu Ngadjui Takuya Koseki Yoshihito Shiono |
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Affiliation: | 1. Département de Chimie Organique, Université de Yaoundé 1, Yaoundé, Cameroun;2. Department of Food, Life, and Environmental Science, Faculty of Agriculture, Yamagata University, Tsuruoka, Yamagata, Japan;3. The United Graduate School of Agricultural Sciences, Iwate University, Morioka, Iwate, Japan;4. Research and Analytical Center for Giant Molecules, Graduate School of Science, Tohoku University, Sendai, Miyagi, Japan |
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Abstract: | Phytochemical investigation of the roots of Albizia chevalieri led to the isolation of two new 5‐deoxyflavan‐3,4‐diol glucosides from roots of A. chevalieri, Chevalieriflavanosides A and B. Their structures were established by 2D NMR techniques, UV, IR, CD, and mass spectrometry. Cytotoxicity of the two compounds was evaluated against acute promyelocytic leukemia HL60 cells. The antibacterial activities of 1 and 2 also were evaluated against Pseudomonas aeruginosa and Staphylococcus aureus using the agar diffusion test. Copyright © 2016 John Wiley & Sons, Ltd. |
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Keywords: | NMR 1H 13C Leguminosae Albizia chevalieri flavan‐3,4‐diols cytotoxicity |
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