Synthesis and characterization of cationic PNA bearing 5-ω-aminopropyl-uracil |
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| Authors: | Paul H Kim Christopher Switzer |
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| Institution: | Department of Chemistry, University of California—Riverside, Riverside, CA 92521, United States |
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| Abstract: | 5-ω-Aminopropyl-uracil bearing PNA monomers are synthesized for solid phase oligomer synthesis using FMOC protection. Several PNA oligomers with differing amounts of aminopropyluracil modification were prepared. These oligomers were found to associate with complementary DNA oligonucleotides. |
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| Keywords: | PNA DNA Origins of life Synthetic biology |
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