Towards the real didemnaketal A: total syntheses of two C-21 stereoisomers of the proposed didemnaketal A |
| |
Authors: | Fu-Min Zhang Yong-Qiang Tu |
| |
Affiliation: | State Key Laboratory of Applied Organic Chemistry & Department of Chemistry, Lanzhou University, Lanzhou 730000, PR China |
| |
Abstract: | Two isomers (3 and 4) with a configuration at C-21 opposite to that proposed for didemnaketal A were synthesized through a process in which the longest linear sequence involved 29 steps. Comparative NMR analysis of these isomers and natural didemnaketal A suggests the possibility of misassignments at other stereocenters in the proposed structure of didemnaketal A. |
| |
Keywords: | Didemnaketal A Total synthesis Isomer Structural reassignment |
本文献已被 ScienceDirect 等数据库收录! |