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Efficient and mild method for preparation of allylic amines from aziridine-2-alcohols using PPh3/I2/imidazole
Authors:Subhash P Chavan  Lalit B KhairnarPrakash N Chavan
Institution:Division of Organic Chemistry, CSIR-NCL (National Chemical Laboratory), Pune 411008, India
Abstract:Allylic amines are synthesized in good to excellent yields by treatment of aziridine-2-alcohols with PPh3/I2/imidazole in THF as solvent under mild conditions.
Keywords:PPh3/iodine/imidazole  Reductive elimination  Chiral aziridine-2-alcohols  Chiral allylic amine
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