A novel four-component synthesis of ethyl 6-amino-4-aryl-5-cyano-2,4-dihydropyrano[2,3-c]pyrazole-3-carboxylates |
| |
| Authors: | VL Gein TM Zamaraeva PA Slepukhin |
| |
| Institution: | 1. Perm Pharmaceutical Academy, Polevaya Street, 2, Perm, Russia;2. Institute of Organic Synthesis, Ural Branch of Russian Academy of Science, Sofya Kovalevskaya Street 22/20, Ekaterinburg, Russia |
| |
| Abstract: | Ethyl 6-amino-4-aryl-5-cyano-2,4-dihydropyrano2,3-с]pyrazole-3-carboxylates were synthesized via a four-component reaction of the sodium salt of diethyloxaloacetate, an aromatic aldehyde, hydrazine hydrate, and malononitrile. The products were obtained in moderate to high yields. |
| |
| Keywords: | Multicomponent reaction Sodium diethyloxaloacetate Aromatic aldehydes Malononitrile Hydrazine hydrate Pyrano[2 3-c]pyrazoles |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
