Synthesis and fluorescence properties of environment-sensitive 7-(diethylamino)coumarin derivatives |
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Authors: | Stane Pajk |
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Affiliation: | Faculty of Pharmacy, University of Ljubljana, Ašker?eva 7, SI-1000 Ljubljana, Slovenia; Laboratory of Biophysics, Condensed Matter Physics Department, ‘Jo?ef Stefan’ Institute, Jamova 39, SI-1000 Ljubljana, Slovenia |
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Abstract: | By linking 7-(diethylamino)coumarin and different aromatic groups via an oxazole moiety, a small series of new environment-sensitive fluorophores have been synthesized. They display varying degrees of environment-sensitivity, depending on the aromatic group present on the oxazole ring. Additionally, these coumarin-based fluorophores show considerably better photostability compared to the nitrobenzoxadiazole fluorophore, and offer a good starting point for the further development of these fluorophores into environment-sensitive membrane probes or for other applications requiring sensitivity to the environment. |
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Keywords: | Fluorescence Environment-sensitive Coumarin Photostability |
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