Practical synthesis of adenosine 3′,5′-cyclic monophosphorodithioate |
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| Authors: | Atsuya Fukuhara Hiroki Morita Kin-ichi Oyama Masaki Tsukamoto |
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| Affiliation: | 1. Graduate School of Information Science, Nagoya University, Chikusa, Nagoya 464-8601, Japan;2. Chemical Instrumentation Facility, Research Center for Materials Science, Nagoya University, Nagoya 464-8602, Japan |
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| Abstract: | Adenosine 3′,5′-cyclic monophosphorodithioate (cAMPS2), which has two exocyclic sulfurs directly attached to phosphorus, was synthesized from adenosine phosphoramidite by intramolecular cyclization employing the phosphotriester method as a key step. |
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| Keywords: | Adenosine 3&prime ,5&prime -cyclic monophosphorodithioate Phosphoramidite Phosphotriester method Adenosine 3&prime ,5&prime -cyclic monophosphate |
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