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A novel synthesis of new 2-aryl-6-(arylamino)-1H-imidazo[1,2-b]pyrazole-7-carbonitrile derivatives
Authors:Jabbar Khalafy  Ahmad Poursattar MarjaniFatemeh Salami
Institution:Department of Chemistry, Faculty of Science, Urmia University, Urmia 57154, Iran
Abstract:New 2-aryl-6-(arylamino)-1H-imidazo1,2-b]pyrazole-7-carbonitriles are synthesized in good yields, via cyclocondensation of 5-amino-1-(2-oxo-2-arylethyl)-3-(arylamino)-1H-pyrazole-4-carbonitriles, which are prepared by the reaction of 5-amino-3-arylamino-1H-pyrazole-4-carbonitriles and α-bromoacetophenone derivatives in the presence of K2CO3 using acetone as the solvent.
Keywords:1H-Imidazo[1  2-b]pyrazole  Cyclocondensation  5-Amino-1H-pyrazoles  α-Bromoacetophenones
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