A highly efficient synthesis of imidazo-fused polyheterocycles via Groebke–Blackburn–Bienaymè reaction catalyzed by LaCl3·7H2O |
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| Authors: | Anand H Shinde Malipatel SrilaxmiBishnupada Satpathi Duddu S Sharada |
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| Institution: | Department of Chemistry, Indian Institute of Technology (IIT) Hyderabad, Ordnance Factory Estate, Yeddumailaram 502205, Medak District, Telangana, India |
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| Abstract: | A highly efficient and mild protocol for the synthesis of imidazo-fused polyheterocycles via Groebke–Blackburn–Bienaymè reaction under the influence of catalytic amount of lanthanum chloride heptahydrate has been described. A wide range of nitrogen-enriched polyheterocycles are synthesized with high yields under neat conditions. |
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| Keywords: | Imidazo[1 2-a]pyridine Lanthanum chloride-catalyzed Solvent-free Multicomponent reaction |
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