Three new glutarimide alkaloids from Croton cuneatus |
| |
Authors: | Suárez Alírica I Blanco Zuleyma Delle Monache Franco Compagnone Reinaldo S Arvelo Francisco |
| |
Institution: | Facultad de Farmacia, Universidad Central de Venezuela, Apartado 40109, Caracas, Venezuela. asuarez@strix.ciens.ucv.ve |
| |
Abstract: | Analysis of the dichloromethane extract of the aerial parts of Croton cuneatus led to the isolation of the new glutarimide alkaloids: julocrotol (1), isojulocrotol (2), and julocrotone (3) along with the known compounds julocrotonine (4), lichexanthone (5) and selin-11-en-4alpha-ol (6). The structures of the new compounds were established by spectral methods. The in vitro cytotoxic activity of Compounds 1-6 was evaluated against six human tumor cells lines. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|