Densely functionalized 1,2-dihydrobenzo[b][1,6]naphthyridines: one-pot synthesis via sequential Ugi and Heck reactions |
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Authors: | Mrityunjaya Asthana Neha SharmaRadhey M Singh |
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Institution: | Department of Chemistry, Centre of Advanced Study, Banaras Hindu University, Varanasi 221005, UP, India |
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Abstract: | A facile one-pot synthesis of functionalized 1,2-dihydrobenzob]1,6]naphthyridines is described via sequential Ugi four components using 2-chloroquinoline-3-carboxaldehydes, allyl amine, acetic acid, isocyanides and ligand free Heck reactions in good yields. |
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Keywords: | Benzo[b][1 6]naphthyridines One-pot Ugi reaction Heck reaction Functionalized |
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