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Densely functionalized 1,2-dihydrobenzo[b][1,6]naphthyridines: one-pot synthesis via sequential Ugi and Heck reactions
Authors:Mrityunjaya Asthana  Neha SharmaRadhey M Singh
Institution:Department of Chemistry, Centre of Advanced Study, Banaras Hindu University, Varanasi 221005, UP, India
Abstract:A facile one-pot synthesis of functionalized 1,2-dihydrobenzob]1,6]naphthyridines is described via sequential Ugi four components using 2-chloroquinoline-3-carboxaldehydes, allyl amine, acetic acid, isocyanides and ligand free Heck reactions in good yields.
Keywords:Benzo[b][1  6]naphthyridines  One-pot  Ugi reaction  Heck reaction  Functionalized
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