Silver-catalyzed 2-isocyanobiaryls insertion/cyclization with phosphine oxides: synthesis of 6-phosphorylated phenanthridines |
| |
| Authors: | Jia-Jia Cao Tong-Hao ZhuZheng-Yang Gu Wen-Juan HaoShun-Yi Wang Shun-Jun Ji |
| |
| Affiliation: | Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China |
| |
| Abstract: | A silver-catalyzed 2-isocyanobiaryls insertion/cyclization with phosphine oxides was described for the construction of the 6-phosphorylated phenanthridines through radical addition of in situ formed P-centered radical to 2-isocyanobiphenyls and homolytic aromatic substitution process. The reactions could proceed smoothly to give the desired 6-phosphorylated phenanthridines promoted by AgOAc (20 mol %) with PhI(OAc)2 (3.0 equiv). |
| |
| Keywords: | Silver-catalyzed Isocyanobiaryls insertion Phosphine oxides 6-Phosphorylated phenanthridines |
| 本文献已被 ScienceDirect 等数据库收录！ |
