Total synthesis of (+)-anamarine |
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Authors: | Kavirayani R Prasad S Mothish Kumar |
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Institution: | Department of Organic Chemistry, Indian Institute of Science, Bangalore 560 012, Karnataka, India |
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Abstract: | An enantiospecific total synthesis of polyhydroxy δ-pyrone natural product (+)-anamarine is accomplished. The main features of the synthesis include the stereoselective reduction of the ketone obtained by the desymmetrization of the bis-dimethyl amide of tartaric acid and further elaboration involving asymmetric Brown's allylation and ring closing metathesis. |
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Keywords: | Anamarine Polyhydroxy lactone δ-Pyrone |
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