Sustainable,mild and efficient p-methoxybenzyl ether deprotections utilizing catalytic DDQ |
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| Authors: | Katie Walsh Helen F Sneddon Christopher J Moody |
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| Institution: | 1. School of Chemistry, University of Nottingham, University Park, Nottingham NG7 2RD, UK;2. Green Chemistry Performance Unit, GlaxoSmithKline R&D Ltd, Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, UK |
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| Abstract: | A procedure for the selective deprotection of p-methoxybenzyl ethers using catalytic amounts of DDQ and of sodium nitrite, with oxygen as the terminal oxidant, is reported. |
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| Keywords: | Deprotection Oxidation Quinone |
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