Copper(I)-catalyzed synthesis of 1-arylpyrazolo[5,1-b]quinazolin-9(1H)-one via intramolecular alkyne hydroamination |
| |
| Authors: | Dong-Sheng Chen Mei-Mei ZhangYu-Ling Li Yun LiuXiang-Shan Wang |
| |
| Institution: | School of Chemistry and Chemical Engineering, Jiangsu Key Laboratory of Green Synthesis for Functional Materials, Jiangsu Normal University, Xuzhou, Jiangsu 221116, PR China |
| |
| Abstract: | The 1-arylpyrazolo5,1-b]quinazolin-9(1H)-one derivatives were obtained via intramolecular alkyne hydroamination reaction of 2-amino-N′-arylbenzohydrazide and alkynal diethyl acetal in the presence of CuBr and Cs2CO3. This new procedure provides an efficient method to construct fused tricyclic heterocycle containing both pyrazole and quinazoline analogues. |
| |
| Keywords: | Pyrazoloquinazoline CuBr-Catalyzed Alkyne hydroamination Synthesis |
| 本文献已被 ScienceDirect 等数据库收录！ |
