Convenient DABCO-catalyzed one-pot synthesis of multi-substituted pyrano[2,3-c]pyrazole dicarboxylates |
| |
| Authors: | Ablajan Keyume Zeynepgul EsmayilLiju Wang Feng Jun |
| |
| Affiliation: | Key Laboratory of Oil & Gas Fine Chemicals, Ministry of Education & Xinjiang Uyghur Autonomous Region, College of Chemistry and Chemical Engineering, Xinjiang University, Urumqi 830046, PR China |
| |
| Abstract: | We developed an efficient and simple one-pot synthesis of functionalized multi-substituted 2,4-dihydro-pyrano[2,3-c]pyrazole dicarboxylates from β-ketoesters, hydrazine, dimethyl acetylenedicarboxylate and malononitrile in EtOH. This four-component one-pot reaction carried out in the presence of DABCO catalyst showed advantages over a one-pot three-component method in its simple procedure, high yield and low toxicity. |
| |
| Keywords: | Pyrano[2,3-c]pyrazole Acetylenedicarboxylate Multicomponent reaction One-pot synthesis DABCO |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
