Intra-aneurysmal blood flow based on patient-specific CT angiogram

To discuss the validity of the hemodynamic hypothesis of aneurysm rupture, we used a patient-specific, realistic aneurysm model to reveal the flow structure and wall shear stress distribution in two cases: one with an unruptured aneurysm and the other with a ruptured aneurysm. We used particle imaging velocimetry and laser Doppler velocimetry to measure velocity profiles of intra-aneurysmal flow. Both cases had a circulating flow along the aneurysm wall, although the second case had a recirculating zone only in the minimum phase. Differences in the wall shear stress profile may identify aneurysm rupture.