Calibration of complex mixtures in one sweep |
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Authors: | Igor Bergen Sascha Liedtke Stefanie Güssgen Oliver Kayser Chandrasekhara Hariharan Carolin Drees Wolfgang Vautz |
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Institution: | 1.TU Dortmund, Technical Biochemistry,Dortmund,Germany;2.ION-GAS GmbH, Konrad-Adenauer-Allee 11,Dortmund,Germany;3.Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V,Dortmund,Germany;4.Eye on Air B.V., The Gallery,Enschede,Netherlands |
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Abstract: | The calibration of extremely complex humid gas-phase mixtures – often required in ion mobility spectrometry applications – is challenging, even when high-performance calibration gas generators such as HovaCAL® are applied. Here, we describe an approach to develop and apply mixtures of VOCs in one channel of such a calibration gas generator for a complex calibration in one sweep. As an example, a mixture of so-called “Signs of Life” – compounds available in the exhaled breath and/or in the sweat of everybody was used. The procedure of developing the appropriate mixture and the results of a successful calibration of a GC-ion mobility spectrometer are presented. |
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