Reaction between the OH group of hydroxyproline and diisocyanate catalyzed by an organotin compound |
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| Authors: | J J Tondeur G Vandendunghen and M Watelet |
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| Institution: | (1) Université de L'Etat, 19, Av. Maistriau, B-7000 Mons, (Belgium) |
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| Abstract: | We have studied the kinetics of the reaction of L-hydroxyproline with OCH(CH2)6NCO, catalyzed by organotin, avoiding side reactions by protecting the other active hydrogens of the aminoacid, and comparing it with the MeOH/n-BuNCO system.
            L-      -    -OCN(CH2)6NCO,  , .      .    - .
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