Synthesis and antimicrobial activity of N,6-diaryl-4-methyl-2-thioxo-1,2,3,6-tetrahydropyrimidine-5-carboxamides |
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| Authors: | V. L. Gein T. M. Zamaraeva A. V. Balandina M. V. Dmitriev |
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| Affiliation: | 1.Perm State Pharmaceutical Academy,Ministry of Healthcare of the Russian Federation,Perm,Russia;2.Perm State National Research University,Perm,Russia |
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| Abstract: | Three-component reactions of acetoacetic acid N-arylamides, aromatic aldehydes, and thiourea afforded N,6-diaryl-4-methyl-2-thioxo-1,2,3,6-tetrahydropyrimidine-5-carboxamides. Structure and antimicrobial activity of the compounds obtained were examined. |
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