C12A7-O-纳米材料的制备及抗菌活性

利用溶胶-凝胶法制备了C12A7-O-{[Ca24Al28O64]4+·4(O-)}纳米材料. 采用X射线衍射、电子顺磁共振及透射电子显微镜等手段对制备的材料进行了表征. 结果表明, 在最佳焙烧条件(1150 ℃, 6 h)下制备的材料平均粒径为74 nm, 并具有晶胞参数为(1.199±0.004) nm的C12A7(Ca12Al14O33)笼状结构, 材料内包含浓度高达1.2×1020 cm-3的氧负离子(O-). 初步研究结果表明, 合成的C12A7-O-纳米材料具有良好的广谱抗菌作用.

Preparation and Bactericidal Activity of C12A7-O~-Nanoparticles

C12A7-O-{[Ca24Al28O64]4+·4(O-)} nanoparticles were prepared by sol-gel method. The synthesized C12A7-O- nonaparticles were investigated by X-ray diffraction, electron spin resonance and transmission electron microscopy. The antibacterial test of the C12A7-O- nonaparticles was also performed against E. coli(DH5α), S. aureus(ATCC 6538) and B. subtilis(ATCC 9372). The results show that the best condition for preparing C12A7-O- nanoparticles was sintering at 1150 ℃ for 6 h in oxygen ambience. The mean particle size of the C12A7-O- nanoparticles was 74 nm, and the cell parameter of the C12A7(Ca12Al14O33)cage with a O-concentration of 1.2×1020 cm-3 was (1.199±0.004) nm. The C12A7-O- nanoparticles also exhibited excellent broad-spectrum antibacterial activity. The unique features of present material such as thermal stability, environment-friendly property and safety, could be potentially utilized in antibacterial materials.