Determination of Azaleptine by Direct Potentiometry and Amperometric Titration

The conditions for the formation of a poorly soluble ion pair of azaleptine and the phosphomolybdic anion and its physicochemical properties were studied by UV and IR spectroscopy. The composition of the ion pair (Az₃PMo₁₂O₄₀) was determined by amperometric titration. The compound obtained was used as an ionophore in the development of a film ion-selective electrode reversible to azaleptine cations. Procedures were developed for the determination of azaleptine in medicinal preparations by direct potentiometry and amperometric titration.