Improvement on dynamic elastic interpolation technique for reconstructing 3-D objects from serial cross sections [biomedical application

An improved method for automatically reconstructing a three-dimensional object from serial cross sections is presented. The method improves the dynamic elastic contour interpolation technique. There are two major improvements: (1) in the case of branching that involves concave contours, instead of pairwise interpolation between the start contour and each goal contour, the goal image is considered globally and local constraints are imposed on the forces exerting upon the vertices; and (2) it takes the continuity of high-order derivatives into consideration and incorporates the schemes of spline theory, quadratic-variation-based surface interpolation, and finite-element-based multilevel surface interpolation to create smoother surfaces of the reconstructed object. Based on the output from the preliminary processing, two alternatives, a quadratic-variation-based surface interpolation algorithm and a finite-element-based multilevel surface interpolation algorithm, can be adopted to obtain the final surface representation