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Solid-phase synthesis of 2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine derivatives
Authors:Zhang LiuWenteng Chen  Marc A GiulianottiRichard A Houghten
Institution:Torrey Pines Institute for Molecular Studies, 11350 SW Village Parkway, Port St. Lucie, FL 34987, USA
Abstract:We have developed an efficient solid-phase synthetic approach for the synthesis of 2,3,4,5-tetrahydro-1H-benzoe]1,4]diazepine derivatives. The methodology is of value for high throughput synthesis of these potentially bioactive molecules.
Keywords:Solid-phase  Diazepine  Heterocycle
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