COMPARISON OF FREE RADICALS PRODUCED BY LASER AND ULTRASOUND ABLATION OF CARDIOVASCULAR TISSUE |
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| Authors: | R. H. Clarke K. Nakagawa J. M. Isner |
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| Affiliation: | Department of Chemistry, Boston University, Boston, MA 02215, USA and Department of Medicine, New England Medical Center, Boston, MA 02111, USA |
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| Abstract: | Abstract— We have used the method of spin trapping and EPR to study the nature of the free radicals produced by laser photoreaction of cardiovascular tissue. The results obtained with argon-ion (cw) and excimer (pulsed) lasers have been compared with radicals produced by ultrasonic disruption of the tissue samples. These comparative studies provide an understanding of the mechanism by which laser light energy effects photoablation of cardiovascular tissue in the pulsed vs cw mode of operation. |
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