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Specific absorption parameters for uranium octoxide and dioxide applicable to the ICRP Publication 66 respiratory tract model
Authors:L Bertelli  A Puerta  M E Wrenn  J L Lipsztein
Institution:(1) Institute of Radiation Protection and Dosimetry, National Nuclear Energy Commission, Av. Salvador Allende s/n, Cx. Postal 37750, CEP 22780-160 Rio de Janeiro, RJ, Brazil;(2) Institute of Nuclear Sciences and Alternative Energies, Santafe de Bogota D. C., Colombia;(3) Radiation Surveillance Associates, 1230 Princeton Ave., Salt Lake City, Utah, USA
Abstract:Literature data from in vivo chest measurements and urinary excretion rates of individuals exposed to U3O8 and UO2 were used to compare the results predicted by different models with empirical observations in humans. As a result the use of the respiratory tract model proposed in ICRP Publication 66 with its default absorption parameters underestimates urinary excretion of inhaled U3O8 and UO2. The new respiratory tract model also overpredicts the Fecal/Urine activity ratio, independently of the systemic model. For U3O8 and UO2 the choice of systemic model has very little influence on the predicted urinary excretion of inhaled compounds. On the other way, the choice of the respiratory tract model does influence the predicted urinary excretion significantly. In this work specific absorption parameters for U3O8 and UO2 were derived to be used in the respiratory tract model proposed in ICRP Publication 66. The predicted biokinetics of these compounds were compared with those derived for Type M and Type S compounds of uranium.
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