Metal 2-Hydroxy-1-Naphthaldehyde Thiosemicarbazone (Me-HNT) Complexes-A New Kind of Biomimic Enzyme Catalyst

Enzymes have been widely used in analytical biochemistry and have considerableadvantages of rapidity and high selectivity'-', but they are expensive and their solutions arequite unstable. So study of biomimic enzyme become an important branch of enzyme,analysis'-'. Metal complexes are important mimetic resources, e-g. the metalloporphyrins.(MPs) system has been used as the model of mimic peroxidase'. As common ligands,Schiffbases are easy to be synthesized, dissolved and are widely used in me…

Metal 2-Hydroxy-1-Naphthaldehyde Thiosemicarbazone (Me-HNT) Complexes-A New Kind of Biomimic Enzyme Catalyst

Metal (Me=Fe(III), Mo(VI), Mn(II), Co(II), Ni(II), Zn(II) and Cu(II)) 2-hydroxy-1 naphthaldehyde thiosemicarbazone complexes (MeHNT) were synthesized and used as mimic-enzyme catalysts to mimic the active group of horseradish peroxidase (HRP). The results showed that FeHNT. Mo-HNT are effective catalysts, which have similar catalytic activity as HRP. The sequence of catalytic activities of tested biomimic peroxidas is Mo-HNT> Fe-HNT > Zn-HNT > Ni-HNT > MnHNT. Among them. Fe-HNT is used as a mimic-enzyme catalyst in determination of ascorbic acid and glucose by coupling the catalytic reaction of glucose oxidase.