首页 | 本学科首页   官方微博 | 高级检索  
     检索      

结构DNA纳米技术应用新进展
作者单位:
基金项目:the Scientific Research Foundation for Returned Overseas Chinese Scholars, China(2014010615);National Natural Science Foundation of China(21603276);National Natural Science Foundation of China(21303267);Natural Science Foundation of Shandong Province, China(ZR2016BL14);Fundamental Research Funds for the Central Universities, China(15CX05027A);Fundamental Research Funds for the Central Universities, China(16CX05013A)
摘    要:DNA具有非凡的分子识别性能和显著的结构特征,这使得它在材料的纳米级调控方面具有独特的优越性,在许多领域也展现出广阔的应用前景。本文从模块化DNA自组装和DNA折纸术两个方面综述了近些年DNA纳米技术,包括近年来DNA纳米技术中比较新型的组装方法;并从DNA纳米结构作为模板定位纳米粒子和蛋白以及用于生物医药等方面介绍了DNA纳米技术的应用;同时,对DNA纳米技术发展及应用进行了展望。

关 键 词:DNA纳米技术  自组装  DNA模块  DNA折纸术  靶向给药  
收稿时间:2017-02-16

Application of Structural DNA Nanotechnology
Authors:Hong-Zhi ZHANG  Zhi-Qing ZHANG  Fang WANG  Ting ZHOU  Xiu-Feng WANG  Guo-Dong ZHANG  Ting-Ting LIU  Shu-Zhen LIU
Institution:
Abstract:DNA possesses extraordinary molecular recognition properties and remarkable structural features in the nano-level material regulation fields, which have shown enormous applications in many areas. In this review, we focus on DNA nanotechnology, including aspects ranging from modular DNA self-assembly to DNA origami, in addition to the recently reported novel assembly methods. Moreover, we summarize some applications of DNA nanotechnology, such as DNA-directed nanoparticle spatial positioning and orientation, and well-defined assembly of proteins on the DNA structure, as well as its uses, such as in the biomedical field, etc. The development and potential applications of DNA nanotechnology are also discussed.
Keywords:DNA nanotechnology  Self-assembly  DNA module  DNA origami  Targeted drug delivery  
本文献已被 CNKI 等数据库收录!
点击此处可从《物理化学学报》浏览原始摘要信息
点击此处可从《物理化学学报》下载免费的PDF全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号