On the Reaction between Alkyl Isocyanides and Ethynyl Phenyl Ketone in the Presence of N,N′-Dimethylbarbituric Acid |
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| Authors: | Issa Yavari Mohammad Anary-Abbasinejad Abdolali Alizadeh |
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| Institution: | (1) Department of Chemistry, University of Tarbiat Modarres, Tehran, Iran, IR |
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| Abstract: | Summary. The reactive 1:1 intermediate produced in the reaction between alkyl isocyanides and ethynyl phenyl ketone was trapped with
N,N ′-dimethylbarbituric acid to produce alkyl 1,3-dimethyl-2,4-dioxo-7-phenyl-1,3,4,5-tetrahydro-2H-pyrano2,3-d]pyrimidine-5-carboxamides in good yields.
Corresponding author. E-mail: isayavar@yahoo.com
Received January 8, 2002. Accepted January 14, 2002 |
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| Keywords: | ,Alkyl isocyanides, Ethynyl phenyl ketone, N,N ,′,-Dimethylbarbituric acid, Pyrimidine derivatives, Ugi reaction |
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