| 血浆中丁丙诺啡提取方法研究 |
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| 引用本文： | 刘冬娴,贺江南.血浆中丁丙诺啡提取方法研究[J].光谱实验室,2007,24(2):274-277. |
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| 作者姓名： | 刘冬娴 贺江南 |
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| 作者单位： | 湖南公安高等专科学校,长沙市远大三路,410006;湖南公安高等专科学校,长沙市远大三路,410006 |
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| 摘 要： | 报道了液相萃取法、固相萃取法提取血浆中丁丙诺啡的方法.血浆中添加丁丙诺啡,液相萃取时调pH至7用三氯甲烷提取、固相萃取时调pH至10.8用401有机担体作吸附剂、用三氯甲烷作洗脱剂,GC/NPD法进行检测.液相萃取血浆中丁丙诺啡萃取率可达85.8%以上,固相萃取血浆中丁丙诺啡萃取率可达87.7%以上.该提取方法萃取率高,可用于血浆中丁丙诺啡的提取.
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| 关 键 词： | 丁丙诺啡 固相萃取 液相萃取 血浆 |
| 文章编号： | 1004-8138(2007)02-0274-04 |
| 修稿时间： | 2006-12-13 |
A Study on Extraction Method of Buprenorphine in Plasma |
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| LIU Dong-Xian,HE Jiang-Nan.A Study on Extraction Method of Buprenorphine in Plasma[J].Chinese Journal of Spectroscopy Laboratory,2007,24(2):274-277. |
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| Authors: | LIU Dong-Xian HE Jiang-Nan |
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| Institution: | Department of Criminal Technology,Hunan Public Security College,Changsha 410006 ,P. R. China |
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| Abstract: | Buprenorphine was extracted from plasma with chloroform at pH7 or with organic support 401 at pH10.8,and eluted with chloroform,finally determined by GC-NPD.The recovery are 85.8% in liquid phase extraction and 87.7% in the solid phase extraction,respectively.The two methods are simple and accurate methods for the separation of buprenorphine from plasma. |
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| Keywords: | Buprenorphine Solid-Phase Extraction Solution-Phase Extraction Plasma |
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