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| 傅里叶变换红外光谱用于胃镜样品的检测 | |
| 引用本文： | 孙学军,李庆波,石景森,任予,张元福,徐端夫,吴瑾光. 傅里叶变换红外光谱用于胃镜样品的检测[J]. 光谱学与光谱分析, 2004, 24(8): 933-935 |
| 作者姓名： | 孙学军 李庆波 石景森 任予 张元福 徐端夫 吴瑾光 |
| 作者单位： | 1. 西安交通大学第一医院，陕西 西安 710061 2. 北京大学化学与分子工程学院，稀土材料化学及应用国家重点实验室，北京 100871 3. 中国科学院化学研究所，北京 100080 |
| 基金项目： | 国家自然科学基金 (30 371 60 4 )，国家重点基础研究发展规划(2 0 0 2CCA0 1 90 0 )，教育部博士点基金，陕西省科学技术研究发展计划项目(2 0 0 3K1 0 G37)资助 |
| 摘 要： | 应用傅里叶变换红外光谱(FTIR) 法对184例不同病理状态的胃镜下活检组织样品进行检测和分析，结果表明，慢性浅表性胃炎的基本谱图特征包括：较强的酰胺Ⅱ带;1 460 cm-1处的峰强高于1 400 cm-1处的峰强。典型的胃癌组织的谱图特征包括：较低的酰胺Ⅱ带;1 460 cm-1处的峰强低于1 400 cm-1处的峰强;1 300 cm-1的峰强明显增加。慢性萎缩性胃炎呈现出部分胃癌的光谱特征。这一结果表明，应用FTIR可以对胃镜下活检的小块组织进行鉴别诊断。 |
| 关 键 词： | FTIR 胃镜 慢性胃炎 肿瘤 检测 |
| 文章编号： | 1000-0593(2004)08-0933-03 |
| 收稿时间： | 2004-02-08 |
| 修稿时间： | 2004-02-08 |
FTIR Spectroscopic Study on Gastric Tissue Samples from Gastroscopy |
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| SUN Xue jun ,,LI Qing bo ,SHI Jing sen ,REN Yu ,ZHANG Yuan fu ,XU Duan fu ,WU Jin guang. FTIR Spectroscopic Study on Gastric Tissue Samples from Gastroscopy[J]. Spectroscopy and Spectral Analysis, 2004, 24(8): 933-935 | |
| Authors: | SUN Xue jun LI Qing bo SHI Jing sen REN Yu ZHANG Yuan fu XU Duan fu WU Jin guang |
| Affiliation: | 1. First Hospital of Xi'an Jiaotong University, Xi'an 710061, China2. The State Key Laboratory of Rare Earth Materials Chemistry and Applications, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China3. Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China |
| Abstract: | A total of 184 specimens from gastroscopy were studied using Fourier transform infrared(FTIR) spectroscopy. The spectra of small sized gastric endoscope samples with high quality were measured using the modified FTIR spectrometer with a MCT detector. The results show that the spectra of chronic superficial gastritis are similar to those of the normal block tissue in our previous study. But there are significant differences in band location and relative intensity between the spectra of chronic superficial gastritis and those of normal gastric tissues. Similarly, the differences exist in the spectra of chronic atrophic gastritis and those of malignant gastric tissues. In addition, the subtraction technique can provide more information to identify well the gastric samples of chronic atrophic gastritis, superficial gastritis and gastric cancer from endoscope the detection. These results indicate that FTIR spectroscopy exhibits potential to diagnose the gastric samples from gastroscopy. |
| Keywords: | FTIR Gastroscopy Chronic gastritis Tumor Detection |
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